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Protease-sparing regimen often abbreviated as PSR, is a method or therapy for treating people infected with HIV that involves a three-drug combination that reduces viral load below the limit of detection while saving protease inhibitors for later use. It is considered a weaker (in terms of quantity and concentration) form of HIV treatment. It has been argued that such a regimen is not as potent as giving HIV patients with the strongest drugs as soon as it is detected. Others believe that this might be considered a long-term strategy in order to reduce the amount of HIV,[1] and in some instances have proven to be successful.[2] See also Protease Women's Interagency HIV Study References ^ Corales RB, Shrestha NK, Taege AJ, et al. (2001). "Protease-sparing regimen in a real-life practice with naïve patients: an equal opportunity approach?". HIV Clin Trials 2 (1): 17–21. PMID 11590510. http://thomasland.metapress.com/openurl.asp?genre=article&issn=1528-4336&volume=2&issue=1&spage=17.  ^ Van der Linden D, Hainaut M, Goetghebuer T, et al. (April 2007). "Effectiveness of early initiation of protease inhibitor-sparing antiretroviral regimen in human immunodeficiency virus-1 vertically infected infants". Pediatr. Infect. Dis. J. 26 (4): 359–61. doi:10.1097/01.inf.0000258626.34984.eb. PMID 17414406. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0891-3668&volume=26&issue=4&spage=359.  http://www.projinf.org/pip/26/pip26i.html http://www.projinf.org/pip/25/pip25a.html "Protease Sparing Regimen in a Real Life Practice with Naive Patients: An Equal Opportunity Approach?". 13th International AIDS Conference. Durban, South Africa. July 9–14, 2000. WePeB4134. http://www.aegis.com/conferences/iac/2000/WePeB4134.html.  http://www.aids-ed.org/aidsetc?page=et-14-00-02 http://www.medscape.com/viewarticle/418668 This immunology article is a stub. You can help Wikipedia by expanding it.v · d · e This medical treatment-related article is a stub. You can help Wikipedia by expanding it.v · d · e